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Best Weight Loss Pills of 2022: Review Top Weight Loss Supplements

February 18, 2022 1:30 am

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Good weight loss pills can kick-start or support your weight loss efforts. How do you know which weight loss pills genuinely help you burn fat and get lean, and which ones are just hype?

Every weight loss pill manufacturer makes the same bold claims, but only some supplements hold up to scrutiny and fast-track your weight loss results.

Which weight loss pills are the best on the market in 2022? We’ve investigated and tested the world’s most widely-used weight loss supplements so that you’ll know what to expect from the weight loss pill you ultimately choose.

The Best Weight Loss Supplements in 2022

You just want to lose weight — and you don’t have time to delve into the fine print. We have researched and tested a variety of weight loss pills on the market in 2022 to discover which supplements will genuinely help you shed your extra pounds.

Only the best made it onto the final list:

  • Exipure
  • Java Burn
  • BioFit
  • Glucotrust
  • Meticore
  • Altai balance
  • Dentitox
  • Glucofort
  • Biotox Gold
  • Acidaburn
  • ReNew Weight Loss Detox
  • ALIVE (TryAlive)
  • ReIgnite
  • Custom keto diet

Not all effective weight loss supplements are pills. The best weight loss powder of 2022 is:

  • Okinawa Flat Belly Tonic

Are you ready to choose the weight loss supplement that best fits your lifestyle and diet? Our ranked guide will make it simple for you.


Exipure has quickly risen to the top, and with good reason. This weight loss supplement, which contains a unique blend of nutrients and natural plant-based ingredients, wages war on the very origin of weight gain.

Exipure capsules do one crucial thing — they boost your low brown fatty tissue levels. The result? With BAT flooding into your body, you’ll be able to burn 300 times the calories you otherwise would.

What’s the secret? Exipure is packed full of natural ingredients that supercharge your weight loss efforts, including:

  • Korean ginseng
  • Perilla
  • Kudzu
  • Holy basil
  • Propolis
  • Quercetin
  • Olive oil extract

Get Exipure for only $59.

Java Burn


Java Burn takes a unique approach. Simply add this weight loss supplement to your morning coffee every day, and wake up to a faster metabolism that supports you in your quest to lose weight. Java Burn makes it easier to burn calories while working out and at rest.

Because this coffee powder acts as a stimulant, you won’t just lose weight. You’ll also feel a welcome energy boost and more mental clarity. Java Burn is meant to promote general well being and is an excellent choice for people who want a weight loss supplement — but who hate taking pills.

This potent formula is proudly manufactured in the United States.



BioFit helps you lose weight by flooding billions of probiotics into your system — with a focus on seven strains of probiotics known to improve digestive health, speed up weight loss, and boost your general health and wellbeing.

Are you ready to get serious results based on the premise that proper health starts within? You have nothing to lose by trying BioFit weight loss pills because BioFit offers a 180-day money-back guarantee.



GlucoTrust is a brand new health supplement from the creators of smash-hit offers including Primal Flow and ED Elixir.

This supplement supports healthy blood sugar levels and weight loss for men and women who have Type II diabetes, or want to manage their blood sugar to protect againt this condition.

It also contains ingredients that support weight loss, since excess weight is one of the primary causes of type 2 diabetes. And it has ingredients that help you to get deeper, more restful sleep, another important factor in losing weight and restoring health. 

This makes GlucoTrust a supplement with extremely broad appeal...


MetiCore is a weight loss formula with a twist. This weight loss pill, which has become wildly popular on the internet, targets your core body temperature. As you gain weight, your body temperature plummets, making it difficult to burn fat. By increasing your core body temperature, MetiCore boosts your metabolism — and unlocks fat-burning abilities you never knew you had.

How? MetiCore’s weight loss formula contains six exceptional ingredients to speed up your metabolism. This weight loss pill is safe for men and women alike, and the fact that it is made in an FDA-registered facility inspires further confidence.



Dentitox pro is a liquid natural health supplement that aims to give you strong gum and teeth. Bad breath is becoming common in the society and this might migh people not want to talk to you.

Dentitox pro has been designed to take your dental health and cleanliness to a new level. This will remove or drastically reduce the risk of bad breath, tooth decay, tooth stain, etc.

This health supplement was put together by Marc Hall who lives in North Carolina. He witnessed the dental problems in the society and saw the need to come up with an all-natural remedy.

This dental health supplement is made from natural plants and elements. These plants are sourced directly from local farmers who make sure the plants reach full maturity. Additionally, these farmers use no fertilisers or chemical treatments.



" This breakthrough formula helps naturally awaken the feedback loop responsible for the blood sugar and healing and regenerative potential that’s lying dormant within you."

Blood Sugar Support

Helps support your blood sugar goals and the body’s natural ability to stay healthy.

Improved Blood Health

Powerful anti-oxidants ingredients that help to support a Blood Circulation.

Vitality & Energy

Improves energetic well-being, combating fatigue and increasing vitality.

Blood Sugar Support

Helps support your blood sugar goals and the body’s natural ability to stay healthy.

Altai Balance


Blood Sugar Support

Helps support your blood sugar goals and the body’s natural ability to stay healthy.

Improved Blood Health

Powerful anti-oxidants ingredients that help to support a Blood Circulation.

Vitality & Energy

Improves energetic well-being, combating fatigue and increasing vitality.

Blood Sugar Support

Helps support your blood sugar goals and the body’s natural ability to stay healthy.

Biotox Gold


Biotox Gold is not your usual weight loss supplement. This tincture — yes, that means it’s a liquid — incorporates a total of 20 different natural ingredients. These plant-based extracts help you detox, culminating in (the manufacturer says) swift weight loss without any effort on your part.

Is Biotox Gold, as the manufacturer claims, more powerful than any diet or exercise on the planet? Maybe not, but this weight loss tincture does come with a 60-day money-back guarantee. As you try Biotox Gold, you’ll have plenty of time to decide whether ordering the discounted multi-bottle package is worth it.



Developed by former Marine sniper Master Sergeant Randy Walker, Acidaburn has become one of the most popular weight loss supplements online in 2022. This fat-burning formula was initially designed to help just one person — the creator’s sister, suffering from severe mental health challenges.

Now, anyone can enjoy the benefits of this fat-burning supplement. Do you feel like your metabolism has slowed, and have your previous weight loss efforts been fruitless? Acidaburn, manufactured by Applied Science Nutrition, will give it a proverbial kick up the behind. Some users have lost 47 lbs with Acidaburn, and maybe you can, too.

ReNew Weight Loss Detox


Who hasn’t dreamed of melting their belly fat without any effort? Online hype is quickly building up around RewNew Weight Loss Detox, a detox-based weight loss formula that aims to get rid of harmful toxins and suppress your appetite to help you shed your extra pounds.

ReNew works for you even if you don’t exercise very often, and alongside a loose weight loss diet, the manufacturer says. You only need to take the weight loss formula every day, which can take as little as 10 seconds.



ALIVE is worth looking into if you’re hoping for near-instant weight loss results. This weight loss pill contains herbs, other plant extracts, vitamins, and minerals to support your body’s natural weight loss mechanisms. Begin taking two ALIVE weight loss capsules every day to burn fat within days.

This modern weight loss supplement with a modern design will set you back $69 per bottle of 60 capsules (a one-month supply).



ReIgnite does a great job illustrating that not all weight loss supplements will be the same in 2022. The most competition relies on stimulants and other fat-burning agents to accelerate weight loss. Not ReIgnite.

ReIgnite promises to boost the health of your mitochondria — which are, as you’ll remember, “the powerhouse of the cell.” By helping your cells heal from within, your body will reach the balance it was meant to have all along, resulting in weight loss. It does this through a unique plant-based and herbal blend.

ReIgnite isn’t a “quick fix.” This weight loss pill takes 90 to 180 to reach its full potential, as the healing mechanism it sets in motion takes time. It’s worth the weight because you can expect better overall health alongside weight loss.

Custom Keto Diet


The ketogenic diet or as like some people prefer to call it; the Keto diet or low carb diet is about consuming a lot of protein and fats but fewer carbs. This diet makes the body send the fats that we consume to the liver, which the latter transform it into energy to keep the body strong and active for a long time without feeling tired quickly. The word ketogenic is derived from the word “ketosis” which means the state of the body when it doesn’t have enough glucose in it to turn it into energy, so it generates ketones that work as an amazing source of energy for both the body and the brain which makes it a great option for losing weight in a short term. The keto diet prevents you from consuming the lot for carbs that are the main reason of gaining weight because the sugar makes you hungry most of the time.

Okinawa Flat Belly Tonic


Okinawa Flat Belly Tonic has become one of the more well-known weight loss powders on the market today, and with good reason. This formula contains powerful weight loss ingredients coupled with nutrients that will boost your energy and reduce inflammation.

Simply drink the Okinawa Flat Belly Tonic by mixing a serving of the weight loss powder into a glass of water in the morning.

How We Ranked the Best Weight Loss Pills of 2022

Every single weight loss pill claims to help you lose weight. No surprise there. The catch? Many weight loss supplements fail to do what they promise. Most could honestly best be described as scams. We analyzed the following factors to ensure that only the best weight loss pills were on our list.

Scientifically-Proven Ingredients

Each of the weight loss supplements that ultimately got a spot on our list contains scientifically shown ingredients to accelerate weight loss in research studies. These ingredients boost the metabolism, promote fat burning, and suppress the appetite.

We gave preference to weight loss products that went through clinical trials and other forms of testing.

Strong Doses

Even the best weight loss ingredients do nothing in microscopic doses. A long list of science-backed ingredients will not do any good if the quantities are too weak.

Transparent Advertising

Some weight loss pill manufacturers claim that they can perform miracles. That’s a red flag. The best weight loss supplements are transparent about their effects and do not promise the impossible.

Formulated or Approved by Doctors

Medical professionals designed the most effective weight loss pills. In other cases, the manufacturer consulted a team of doctors, nutritionists, weight loss specialists, or naturopaths. Weight loss pills designed or approved by doctors are more credible than products thrown together by a team of marketers.

User Experience

Weight loss pills don’t just need to be effective for them to work — you also need to take them with ease. If the tablet is too large or its taste is too vile, you’ll quickly abandon the program. That’s why weight loss supplements that are hard to take did not make it onto our list.

Value for Money

Weight loss pills with high-quality ingredients don’t come cheap, and we didn’t shy away from more expensive products that met our stringent quality demands. We did make sure to include a range of price points suitable for every budget.

Money-Back Guarantee

You buy a weight loss supplement for one reason, and one reason alone — to help you lose weight. If the weight loss pill you buy doesn’t deliver the results it promises, you should be able to get your money back. Nearly all of the best weight loss pills now offer a 60-day money-back guarantee. This inspires confidence because the manufacturer believes in their product.

Only the weight loss supplements that met all these demands made it onto the list because they are the best weight loss pills of 2022.

Who Should Consider Taking Weight Loss Pills?

You might consider taking a weight loss pill or using a weight loss powder if you:

  • Are about to start a new diet and exercise routine and want a little help
  • Are already exercising regularly and following a diet and want faster results
  • Want to lose a few pounds without exercising or dieting
  • Committed to burning your fat to reveal your toned muscles
  • Want to eliminate stubborn fat around problem areas like the belly, thighs, and hips — fat that even regular workouts can’t get rid of
  • Need some support to achieve sustainable weight loss

Whether you’ve been trying to lose weight for ages, without the results you hoped for, or you’re just starting, the enhanced results you get with effective weight loss pills can keep you motivated.

How Do Weight Loss Pills Work?

Thanks to the fantastic ingredient variety, no two weight loss pills work the same way. Weight loss pills can help you melt your extra pounds in several ways. They can:

  • Reduce your appetite and fight food cravings, leading to a reduced calorie intake.
  • Boost your metabolism to burn calories more quickly.
  • Prevent you from absorbing the carbs or fat you eat, preventing weight gain.
  • Force your body to burn fat rather than glucose for energy.

All good weight loss pills lead to the same core goal — they help you burn calories faster, leading to weight loss.

What Are the Possible Side Effects of Weight Loss Pills?

No supplement is entirely free from possible side effects. However, if you follow manufacturer instructions closely, you likely won’t experience any.

All weight loss pills contain only ingredients that the FDA has classified as Generally Recognized As Safe (GRAS) and won’t pose a risk to your health unless you misuse them. Minor side effects are possible, however, and they can include:

  • Abdominal discomfort
  • Nausea
  • Headache
  • Fatigue
  • Jitters and anxiety

These side effects will almost always be temporary. You can further reduce your risk of experiencing adverse effects by avoiding ingredients you know you are sensitive to. Many weight loss pills contain caffeine, for instance.

People who have chronic medical conditions or take prescription medications should always consult their healthcare provider before starting with a weight loss pill or powder.

How Should Weight Loss Pills Be Dosed?

Each weight loss pill is unique, and it is crucial to follow manufacturer instructions. Never take more than the recommended dose.

Although it is impossible to cover all the ingredients that weight loss pills may feature, you may want to keep in mind that:

Weight loss pills may contain 50-100 mg of caffeine. A cup of coffee, in comparison, typically has no more than 120 mg.

Garcinia cambogia is most effective at doses of 750-1,500 mg.

However, because each weight loss pill is uniquely formulated, and each ingredient will interact with each component for more effective results, doses can vary widely and still lead to impressive weight loss results.

Is There Scientific Evidence That Weight Loss Pills Work?

Yes. Numerous scientific studies show that weight loss pills can accelerate losing weight. Most of these studies focus on particular ingredients.

Caffeine has been shown to support weight loss in many studies. As an example, this study investigated the effect of caffeine supplements on obese adults. Compared to the control group, the caffeine group lost fat, reduced their waistline, and lost body weight faster.

Fiber, and particularly glucomannan, is another critical weight loss pill ingredient. It has been proven that glucomannan can absorb water and promote weight loss, including in this 2005 study. The participants received a glucomannan supplement and successfully lost weight. Fiber does not only help people lose weight, though — it also promotes better heart health. When you consider that 95 percent of Americans do not get enough dietary fiber, it is easy to see the benefits of fiber in weight loss pills.

Garcinia cambogia will be widely used in weight loss supplements in 2022 due to the presence of a compound known as hydroxycitric acid (HCA). Studies have proven that HCA can reduce fat deposits, as well as that it speeds up the metabolism while reducing appetite. Further research is still needed, but many people have already seen the results for themselves.

EGCG is another potent ingredient in many weight loss pills. Found in green tea extract, EGCG is a compound with antioxidant properties. Research has shown that EGCG may lead to a higher fat-burning rate. In addition, green tea reduces the side effects of caffeine, such as jitters, thanks to the presence of L-theanine.

Conjugated linoleic acid (CLA) is just now gathering momentum as a weight loss supplement. CLA is a fatty acid that can support ketosis. Scientific evidence to support CLA for weight loss is still limited but beginning to emerge.

As you are aware, some of the most potent weight loss pills are prescription-only products. Qsymia is the best example. This medication was FDA-approved as a weight loss pill after phase I and phase II clinical trials found that Qsymia helped people lose, on average, 10 percent of their body weight.

This clinically proven weight loss pill works through phentermine and topiramate, ingredients that lead to quick weight loss results. Qsymia is only available for obese people with a BMI over 30 or patients with chronic health conditions like diabetes or hypertension.

You can enjoy the benefits of weight loss pills even without a prescription, though. Even completely natural ingredients can support you on your weight loss journey, including:

Calcium can help you burn fat and prevent you from gaining more fat by boosting lipolysis.

Capsaicin, a potent ingredient in many weight loss pills, is the same compound that makes chili peppers spicy, and it can induce fat burning and help you lose weight faster by keeping you at a calorie deficit.

Probiotic supplements. These “friendly bacteria” have become famous for people who seek a more robust immune system. Still, they can also help you lose weight by keeping your digestive tract healthy and helping your body digest foods more effectively. Although probiotics are still emerging as a weight loss supplement, Because of growing research supporting the weight loss benefits of probiotics, some studies have already suggested that they can play a crucial role. BioFit, one of the best weight loss pills on the market in 2022, contains nothing but probiotics. This cutting-edge approach is set to become more prevalent in the future.

Less well-known ingredients with some scientific backing include African mango, chromium, forskolin, fucoxanthin, raspberry ketones, and Yohimbe. Further studies are likely to be published soon, but for now, you can already use these ingredients to support you in your weight loss efforts.

In conclusion, a large body of research shows that weight loss pills can play a crucial role in helping you achieve your weight goal. You can burn fat faster, speed up your metabolism, reduce your appetite, and prevent fat absorption with the right ingredients. Weight loss pills can make losing weight both faster and easier.

Weight Loss Pills FAQs

Do you still have questions about weight loss pills? Do you want to know what they can do for you and how they work? Here are the answers to the most frequently asked questions about weight loss pills.

Q: Do I need a prescription for weight loss pills?

A: Some weight loss pills are prescription-only. However, many weight loss pills contain a blend of supplements that can be bought over-the-counter. We can differentiate between weight loss medications and supplements, tablets, but both would be weight loss pills.

Q: How do weight loss pills work?

A: Weight loss pills can help you achieve your weight goal in several ways. Weight loss pills may reduce your appetite, help you feel full for longer, or boost your fat-burning potential. Some weight loss pills act on your hormones. They can achieve all of this with entirely natural ingredients.

Q: What ingredients do weight loss pills contain?

A: Weight loss pills can use tried-and-tested or innovative ingredients to help you lose weight. Some of the most popular elements include caffeine, green tea extract, garcinia cambogia, BHB, and other herbal and plant-based ingredients. Many weight loss supplements contain amino acids, vitamins, and minerals.

Q: Do weight loss pills work?

A: Weight loss pills can help you achieve weight loss more quickly, yes. Almost all weight loss pills will be more effective if you follow a calorie-restricted diet and exercise regularly. However, it will still help if you continue with your everyday lifestyle.

Q: Can I lose weight without dieting or exercising?

A: Weight loss requires a caloric deficit — burning more calories than you take in. A healthy diet and regular exercise are an integral part of any effective weight loss program. Weight loss pills can speed up your metabolism and help you burn fat, and can have a negligible effect on their own. Your results will always be better if you also diet and exercise.

Q: Are weight loss pills safe?

A: Most weight loss supplements are safe if you do not exceed the recommended dosage and follow the instructions. If you have a chronic medical condition, are pregnant, or take medications, always consult your doctor first. Stop taking any weight loss supplements if you experience side effects. People under 18 should not take weight loss pills.

Q: What is the best way to lose weight?

A: Sustainable weight loss is achieved by following a modest calorie-restricted diet combined with an exercise program. Do not follow a crash diet, which will only lead to temporary results. Weight loss pills can be a valuable part of your weight loss program but should not be the entirety of your weight loss plans.

Q: Do all weight loss pills contain caffeine?

A: No. Although caffeine is a popular ingredient in weight loss pills, many caffeine-free weight loss pills are also on the market.

Q: How do I use weight loss pills?

A: Each weight loss pill is different, and it is essential to follow manufacturer instructions. Generally, you will be advised to take one to four capsules per day.

Q: Are weight loss pills a scam?

A: Some weight loss products are scams. However, weight loss pills with scientifically-sound ingredients can help you lose weight. Always buy your weight loss pills from reliable sources to stay safe.

Q: How much weight can I lose with a weight loss pill?

A: Results vary. Some weight loss pills can help you lose up to 5 lbs per week. However, experts agree that weight loss of around 2 lbs per week is the healthiest for most people. This kind of weight loss is sustainable.

Q: Are weight loss pills dangerous?

A: Weight loss pills are generally safe if you do not exceed the recommended dosage. Overdosing on weight loss pills could pose a risk to your health, mainly if the tablets you take include caffeine.

Q: Does fiber help with weight loss?

A: Fiber is one of the most effective weight loss ingredients, as it helps you feel full and supports a healthy digestive system.

Q: Do keto diet pills work?

A: Keto weight loss pills increase the levels of ketone bodies in your blood, which also happens when you reach ketosis after fasting or following a low-carb diet. Research still has not conclusively shown whether these pills help you lose weight.

Q: Can I stop dieting or exercising when taking a weight loss pill?

A: Weight loss pills should support your diet and exercise program, not replace healthy lifestyle habits. Some weight loss supplements claim to help you lose weight without diet and exercise, but this is not recommended.

Q: Is green tea good for weight loss?

A: Green tea contains epigallocatechin gallate (EGCG), which has been shown to promote fat loss.

Q: What are ephedra weight loss pills?

A: Ephedra was commonly used in diet pills in the 1990s, but the ingredient has since been banned. This high-risk ingredient is no longer available on over-the-counter weight loss pills today.

Q: What are the best prescription weight loss pills?

A: Several weight loss medications have been approved by the FDA, including Xenical, Qsymia, Saxenda, Contrave, Phentermine, and Wegovy. These pills require a prescription from a doctor.

Q: What is the best weight loss supplement?

A: Our list is dedicated to helping you figure that out! The best weight loss pills on the market in 2022 include Exipure, Java Burn, and BioFit.

Q: How do I lose tummy fat fast?

A: Stubborn tummy fat can be eliminated through a combination of diet and exercise, and weight loss pills can help support your efforts to lose tummy fat more quickly.

Q: What can I take to get rid of belly fat?

A: You can take any weight loss pills we recommend to help you lose belly fat. You will also need patience and follow a healthy diet and exercise regularly.

Q: Can I burn fat while I sleep?

A: Some weight loss pills burn fat while you sleep by increasing your resting metabolic rate.

Q: What is Orlistat?

A: Alli (orlistat) is one of the most effective weight loss pills of 2022. Orlistat helps stop the absorption of fat, leading to weight loss. This weight loss pill can be prescribed or bought over the counter.

Q: How does caffeine help with weight loss?

A: Caffeine boosts your metabolism and helps you burn fat because it is a powerful stimulant. Caffeine is one of the most researched ingredients in weight loss pills and has repeatedly been effective.

The Best Weight Loss Supplements in 2022 Final Verdict

As you’re gearing up to start a brand new year, you’ve decided it’s time to lose weight and get in shape. Weight loss pills can be an essential part of that journey, helping you stay motivated as you see results more quickly.

Still not sure which weight loss pill is right for you? Our detailed breakdown will help you decide which weight loss supplements complement your goals and lifestyle, allowing you to choose the best weight loss pills for 2022.

RELATED:Best Keto Pills: Top BHB Ketones Ketosis Boosters for Weight Loss

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Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.